The spec sheets list the Malibu Response LX 2008 as sv23 diamond and the Malibu Wakesetter 22 MXZ 2013 as modified vee, so check how each hull rides in the conditions you use before you decide.
On paper these two are close siblings in the size department - Malibu Response LX 2008 at 20,0 ft versus Malibu Wakesetter 22 MXZ 2013 at 22,0 ft. Weight tells a clearer story for trailering families: the Malibu Wakesetter 22 MXZ 2013 tips the scales at 4 400 lbs - 1 950 lbs less than the Malibu Response LX 2008 at 2 450 lbs. That difference is meaningful if you're working within a half-ton or three-quarter-ton truck's tow rating, especially once you factor in a motor, gear, and fuel.
The power gap is worth calling out. Rated to 555 hp, the Malibu Wakesetter 22 MXZ 2013 has a 155-hp advantage over the Malibu Response LX 2008's 400-hp ceiling - enough to notice on acceleration and at cruising speed, particularly with a full passenger load. Fuel capacity breaks the other way: the Malibu Wakesetter 22 MXZ 2013 carries 50 gallons versus 35 gallons in the Malibu Response LX 2008. On a lake day that's negligible, but for coastal cruising or long reservoir runs the extra range matters.
For family outings this is probably the sharpest distinction between the two. The Malibu Wakesetter 22 MXZ 2013 is rated for 15 passengers, while the Malibu Response LX 2008 caps at 8. If you're regularly pulling extended family or a group of friends onto the water, the extra seats on the Malibu Wakesetter 22 MXZ 2013 could be the deciding factor.
Bottom line: Choose the Malibu Wakesetter 22 MXZ 2013 if your priority is putting more people on the water - it handles 15 passengers and at 22,0 ft it has the deck room to back that rating up comfortably. The Malibu Response LX 2008 is the smarter pick if you want a lighter, easier-to-trailer boat rated for 8 that costs less to run day-to-day.